Board Thread:Fanon Canon 2/@comment-25152698-20140928012600/@comment-25152698-20140930203028

For example, Kaguya, who was the first to obtain chakra, passed it onto her children.

The Uchiha and descendants of Indra, the Senju of Asura. They will possess the chakra of Indra and Asura, however minuscule it may be. Sayuri possesses both, as a hybrid of both, and is using the gedo mazo to enhance those cells. (Madara received and strengthened Hashirama's cells using the same method)