Board Thread:Rebirth: Story Time/@comment-4869113-20141109220441/@comment-2089817-20141110012256

Naruto has Shukaku's Magnet Release. Many modern treatments for illnesses rely upon methods revolving around technology that applies electromagnetic principles. Kokuo can heat up his chakra to the "boiling point", which means he could easy burn away any viruses implanted inside him. Kurama has advanced healing, which could ALSO heal the same kind of diseases and ailments. And I mean, I could keep going, but there's three methods right there and I don't think I need to go on more.

Sasuke has Rinnegan, which grants him Deva Path (to blow away any poison smoke attempting to attack him) and Hell Path (which has been shown to remedy the damage inflicted onto an individual's body, as Pain himself demonstrated), among the other four. And he has Sharingan, which would allow him to identify the substance's properties and develop a proper counter to it.

Even assuming all of their skills wouldn't work, Konoha is home to Sakura and Tsunade; the leading two medical ninja in the current shinobi world. No way in utter hell they wouldn't be able to find a way to counteract the poison. As much as I enjoy your creative thinking on the matter, poison is not the route to go. Itachi and Madara did not have these resources at their disposal, so you can't compare the situations.